PROJECT PROPOSAL

TITLE                                          

Comparative analysis of stent design and vessel tissue performance through the novel application of OCT imaging and kinematic analysis.

THESIS/HYPOTHESIS

As a result of this project, I predict to gain ground on developing the various scanning parameters needed to maximize image precision and also hope to continue furthering my understanding of vessel change and deformation through kinematic analysis and in-vivo imagery examination.  The independent and dependent variables also share an important connection in the current need for the improvement of device safety and effectiveness, through the development of new models for vessel motion deformation and materials which best interact with a biological environment.   

INDEPENDENT VARIABLE

In-vivo performance of various stent designs (Varying material, design, strut structure) through OCT image analysis

DEPENDENT VARIABLE(S)

The effectiveness of OCT imaging to allow greater ease and efficiency when analyzing various device images both in and ex vivo.

PURPOSE

As of now, only traditional imaging modalities have been applied in analyzing and diagnosing stent failure and deformation. By applying OCT technology, a more precise and accurate understanding of stent performance may be understood, shedding light on varying failure modes and new variables pertaining to stent effectiveness and durability. 

AUDIENCE

This Project holds possible applications for a wide ranging audience and could shed light on the in-vivo environment surrounding most interventional device implants, a key component to stent performance and efficiency.

CATEGORY

Medical Research in particular, due to the projects emphasis on interventional cardiovascular therapeutics and in-vivo vascular deformation/ change. 

TIMETABLE

I plan to begin a synthesis paper within the next few months and hope to continue the project throughout the year.